角蛋白相关蛋白10-2抗体
规格:1mg/1ml
英文名: KR102
别名: High sulfur keratin-associated protein 10.2; KAP10.2; KAP18-2; KAP18.2; Keratin-associated protein 10-2; Keratin-associated protein 10.2; Keratin-associated protein 18-2; Keratin-associated protein 18
分子量: 26kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KR102
交叉反应:Human,
细胞定位:
角蛋白相关蛋白10-2抗体产品介绍:background: This gene encodes a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This gene encodes a member of the high sulfur KAP family. It is localized to a cluster of intronless KAPs at 21q22.3 which are located within the introns of the C21orf29 gene. [provided by RefSeq, Jul 2008] 角蛋白相关蛋白10-2抗体Function: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. Tissue角蛋白相关蛋白10-2抗体 Specificity: Restricted to a narrow region of the hair fiber cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues. Similarity: Belongs to the KRTAP type 10 family. Gene ID: 386679 Database links: Entrez Gene: 386679 Human SwissProt: P60368 Human Unigene: 664660 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
角蛋白相关蛋白10-2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid