丝氨酸/苏氨酸蛋白激酶KPI2抗体
规格：1mg/1ml
英文名： KPI2
别名： AATYK 2; AATYK2; Apoptosis associated tyrosine kinase 2; Apoptosis-associated tyrosine kinase 2; Brain enriched kinase; Brain-enriched kinase; BREK; CDK5/p35 regulated kinase; CDK5/p35-regulated kinas
分子量： 164kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KPI2
交叉反应：Human,
细胞定位：细胞膜
丝氨酸/苏氨酸蛋白激酶KPI2抗体产品介绍：background: The protein encoded by this gene belongs to the protein kinase superfamily and the protein tyrosine kinase family. It contains N-terminal transmembrane helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity. This protein interacts with several other proteins, such as Inhibitor-2 (Inh2), protein phosphatase-1 (PP1C), p35, and myosin VI. It phosporylates other proteins, and is itself also phosporylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex. This protein involves in nerve growth factor (NGF)-TrkA signalling, and also plays a critical role in endosomal membrane trafficking. Mouse studies丝氨酸/苏氨酸蛋白激酶KPI2抗体 suggested an essential role of this protein in spermatogenesis. [provided by RefSeq, Oct 2009] Function: Phosphorylates PPP1C, phosphorylase b and CFTR. Subcellular Location: Membrane. Tissue Specificity: Mainly expressed in skeletal muscle, and weakly in brain and pancreas. Post-translational modifications: Autophosphorylated. Phosphorylated. Similarity: Belongs to the protein kinase superfamily.丝氨酸/苏氨酸蛋白激酶KPI2抗体 Tyr protein kinase family. Contains 1 protein kinase domain. Gene ID: 22853 Database links: Entrez Gene: 22853 Human Omim: 610989 Human SwissProt: Q8IWU2 Human Unigene: 444179 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
丝氨酸/苏氨酸蛋白激酶KPI2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 激酶和磷酸酶
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid