杀伤细胞凝集素样受体C亚家族成员3抗体
规格：1mg/1ml
英文名： KLRC3
别名： Killer cell lectin like receptor subfamily C member 3; KLRC 3; KLRC3; NK cell receptor E; NKG2 E activating NK receptor; NKG2 E; NKG2 E type II integral membrane protein; NKG2-E type II integral membr
分子量： 27kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLRC3
交叉反应：Human,
细胞定位：细胞膜
杀伤细胞凝集素样受体C亚家族成员3抗体产品介绍：background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. KLRC3 is a member of the NKG2 group which are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The NKG2 gene family 杀伤细胞凝集素样受体C亚家族成员3抗体is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Subcellular Location: Membrane.杀伤细胞凝集素样受体C亚家族成员3抗体 Tissue Specificity: Natural killer cells. Similarity: Contains 1 C-type lectin domain. Gene ID: 3823 Database links: Entrez Gene: 3823 Human Entrez Gene: 58179 Mouse Entrez Gene: 500338 Rat Omim: 602892 Human SwissProt: Q07444 Human Unigene: 654362 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
杀伤细胞凝集素样受体C亚家族成员3抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 细胞膜受体 **细胞 t-**细胞
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid