Kelch样蛋白2抗体
规格：1mg/1ml
英文名： KLHL2
别名： ABP KELCH; Actin binding protein Mayven; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN; OTTHUMP00000219997; OTTHUMP0000
分子量： 66kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLHL2
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：细胞浆
Kelch样蛋白2抗体产品介绍：background: KLHL2 is a 593 amino acid actin-binding protein. Highly expressed in brain, KLHL2 is thought to play a role in the organization of the actin cytoskeleton in brain cells. KLHL3 (kelch-like protein 3), is a 587 amino acid protein active in the protein ubiquitination pathway. KLHL3 is thought to be a substrate-specific adapter of an E3 ubiquitin-ligase complex that mediates the ubiquitination of target proteins, which leads to proteasomal degradation of the target protein. KLHL2 and KLHL3 proteins contain six kelch repeats and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTBKelch样蛋白2抗体domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. Function: May play a role in organizing the actin cytoskeleton of the brain cells. Subcellular Location: Cytoplasm > cytoskeleton. Tissue Specificity: Predominantly expressed in brain. Similarity: Contains 1 BTB (POZ) domain. Contains 6 Kelch repeats. Gene ID: 11275 Database links: Entrez Gene: 11275 Human Omim: Kelch样蛋白2抗体605774 Human SwissProt: O95198 Human Unigene: 388668 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Kelch样蛋白2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 神经生物学 信号转导 结合蛋白 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid