KLHDC8B蛋白抗体
规格：1mg/1ml
英文名： KLHDC8B
别名： FLJ11302; FP17659; Kelch domain containing 8B; Kelch domain containing protein 8B; Kelch domain-containing protein 8B; KLD8B_HUMAN; Klhdc8b; MGC35097; MGC94736.
分子量： 38kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLHDC8B
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞浆
KLHDC8B蛋白抗体产品介绍：background: This gene encodes a protein which forms a distinct beta-propeller protein structure of kelch domains allowing for protein-protein interactions. Mutations in this gene have been associated with Hodgkin lymphoma. [provided by RefSeq, Sep 2010] Subcellular Location: Cytoplasm. In mitotic cells, concentrates in the midbody of the cytoplasmic bridge linking daughter cells as they are about to separate during cytokinesis. DISEASE: Defects in KLHDC8B are a cause of Hodgkin lymphoma (HL) [MIM:236000]. A malignant disease characterized by progressive enlargement of the lymph nodes, spleen and general lymphoid tissue, and the presence of large, usually multinucleate, cells (Reed-Sternberg cells). Reed-Sternberg cells compose only 1-2% of the total tumor cell mass. The remainder is composed of a variety of reactiveKLHDC8B蛋白抗体, mixed inflammatory cells consisting of lymphocytes, plasma cells, neutrophils, eosinophils and histiocytes. Note=A chromosomal aberration disrupting KLHDC8B has been found in a family with the nodular sclerosis type of classic Hodgkin lymphoma. Translocation t(2,3)(q11.2;p21.31). Similarity: Contains 8 Kelch repeats. Gene ID: 200942 Database links: Entrez Gene: 200942 Human Entrez Gene: 78267 Mouse Entrez KLHDC8B蛋白抗体Gene: 306589 Rat Omim: 613169 Human SwissProt: Q8IXV7 Human SwissProt: Q9D2D9 Mouse SwissProt: Q5XIA9 Rat Unigene: 13781 Human Unigene: 283194 Mouse Unigene: 41577 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KLHDC8B蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid