KLHDC10蛋白抗体
规格：1mg/1ml
英文名： KLHDC10
别名： Kelch domain containing 10; Kelch domain-containing protein 10; KIAA0265; KLD10_HUMAN; Klhdc10; OTTHUMP00000212347; PNAS 119; Scruin like at the midline homolog; Slim.
分子量： 49kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human KLHDC10
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位：
KLHDC10蛋白抗体产品介绍：background: KLHDC10 is a 442 amino acid protein that contains six kelch repeats. Expressed in fetal brain, liver, lung, kidney and placenta, KLHDC10 exists as two alternatively spliced isoforms. The gene encoding KLHDC10 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q armKLHDC10蛋白抗体 of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders, including cases of acute myelogenous leukemia and myelodysplasia. Subunit: Interacts with CUL2, TCEB1KLHDC10蛋白抗体 and TCEB2; may be the substrate recognition component of an E3 ubiquitin ligase complex. Subcellular Location: Nucleus Similarity: Contains 6 Kelch repeats. Gene ID: 23008 Database links: Entrez Gene: 23008 Human Entrez Gene: 76788 Mouse SwissProt: Q6PID8 Human SwissProt: Q6PAR0 Mouse Unigene: 520710 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
KLHDC10蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid