细胞表面趋化因子受体2A抗体
规格：1mg/1ml
英文名： CCR2 + CCR5
别名： CC-CKR-2; C-C Chemokine receptor 2A; C C CKR 2; CC chemokine receptor type 2; CC CKR 2; CCCKR2; CCR 2; CCR1L; CCR2A; CCR2B; CCR5L; CD192; CD192 antigen; Chemokine C C motif receptor 2; Chemokine CC Mo
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from mouse CCR2 and
交叉反应：Human, Mouse, Rat, Horse,
细胞定位：
细胞表面趋化因子受体2A抗体产品介绍：background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009]. Function: 细胞表面趋化因子受体2A抗体Receptor for the MCP-1 (JE), MCP-3 (FIC) and MCP-5 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Subunit: Interacts with ARRB1. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Detected in monocyte/macrophage cell lines, but not in nonhematopoietic cell lines. Similarity: Belongs to the G-protein coupled receptor 1 family. Gene ID: 12772 细胞表面趋化因子受体2A抗体Database links: Entrez Gene: 12772 Mouse Entrez Gene: 729230 Human Entrez Gene: 60463 Rat Omim: 601267 Human SwissProt: P41597 Human SwissProt: P51683 Mouse SwissProt: O55193 Rat Unigene: 511794 Human Unigene: 705362 Human Unigene: 6272 Mouse Unigene: 211983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
细胞表面趋化因子受体2A抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞膜受体
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid