**细胞趋化因子CCL21/Exodus 2抗体
规格：1mg/1ml
英文名： CCL21
别名： 6Ckine; Beta chemokine exodus 2; Beta chemokine exodus2; CCL 21; CCL21; Chemokine C C motif ligand 21; Chemokine CC motif ligand 21; CKb 9; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; Exodus
分子量： 15kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human CCL21
交叉反应：Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
细胞定位：分泌型蛋白
**细胞趋化因子CCL21/Exodus 2抗体产品介绍：background: This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member **细胞趋化因子CCL21/Exodus 2抗体of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Jul 2008]. Function: Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Potent mesangial cell chemoattractant. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Subcellular Location: Secreted. Tissue Specificity: Expressed strongly in lung, spleen, thymus, peripheral and mesentric lymph **细胞趋化因子CCL21/Exodus 2抗体nodes. Also expressed in the testis, kidney, liver, and heart. DISEASE: Note=Mice carrying an autosomal recessive mutation designated paucity of lymph node T-cells (plt) show dramatically reduced numbers of T-cells in lymph nodes, Peyer patches, and the white pulp of the spleen. Plt seems to correspond to Scya21b. Similarity: Belongs to the intercrine beta (chemokine CC) family. Gene ID: 6366 Database links: Entrez Gene: 6366 Human Omim: 602737 Human SwissProt: O00585 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
**细胞趋化因子CCL21/Exodus 2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 **学 转录调节因子
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid