A型流感病毒核输出蛋白抗体
规格：1mg/1ml
英文名： Influenza A Nuclear export protein
别名： NS1; NEP_I97A1; Nuclear export protein; NEP; Non-structural protein 2; NS2. NS1A.
分子量： 14kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from Influenza A In
交叉反应：Influenza A
细胞定位：细胞核
A型流感病毒核输出蛋白抗体产品介绍：background: Mediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins, RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs to which the M1 protein is bound. Because the M1 protein is not available in large quantities until the later stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the nucleus before sufficient quantities of viral mRNA and progeny genomic RNA have been synthesized. Furthermore, the RNPs enters the cytoplasm only when they have associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced. Function: ediates the nuclear export of encapsidated genomic RNAs (ribonucleoproteins,A型流感病毒核输出蛋白抗体 RNPs). Acts as an adapter between viral RNPs complexes and the nuclear export machinery of the cell. Possesses no intrinsic RNA-binding activity, but includes a C-terminal M1-binding domain. This domain is believed to allow recognition of RNPs to which the M1 protein is bound. Because the M1 protein is not available in large quantities until the later stages of infection, such an indirect recognition mechanism probably ensures that genomic RNPs are not exported from the nucleus before sufficient quantities of viral mRNA and progeny genomic RNA have been A型流感病毒核输出蛋白抗体synthesized. Furthermore, the RNPs enters the cytoplasm only when they have associated with the M1 protein that is necessary to guide them to the plasma membrane. May down-regulate viral RNA synthesis when overproduced (By similarity). Subunit: Binds M1 protein. May interact with human nucleoporin RAB/HRB and exportin XPO1/CRM1 (By similarity). Subcellular Location: Virion (Potential). Host nucleus (By similarity). Similarity: Belongs to the influenza viruses NEP family. Gene ID: 956532 Database links: Entrez Gene: 956532 Influenza A SwissProt: P03508 Influenza A Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
A型流感病毒核输出蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**及病毒
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid