线粒体内膜蛋白酶样IMP2抗体
规格:1mg/1ml
英文名: IMMP2L
别名: EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP
分子量: 20kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human IMMP2L
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位:
线粒体内膜蛋白酶样IMP2抗体产品介绍:background: This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011] Function: The mitochondrial inner membrane peptidase (IMP) complex generates mature, active proteins in the mitochondrial intermembrane space by proteolytically removing the mitochondrial targeting presequence of nuclear-encoded proteins. IMMPL1 and IMMPL2 are the catalytic subunits of the IMP complex. Subunit: Heterodimer of 2 subunits, IMMPL1 and IMMPL2 (By similarity).线粒体内膜蛋白酶样IMP2抗体 Subcellular Location: Mitochondrion inner membrane; Single pass membrane protein. Tissue Specificity: Expressed in all tissues tested except ***** liver and lung. DISEASE: Gilles de la Tourette syndrome (GTS) [MIM:137580]: Neurologic disorder manifested particularly by motor and vocal tics and associated with behavioral abnormalities. Note=The disease may be caused by mutations 线粒体内膜蛋白酶样IMP2抗体ffecting the gene represented in this entry. Similarity: Belongs to the peptidase S26 family. IMP2 subfamily. Gene ID: 83943 Database links: Entrez Gene: 83943 Human Omim: 605977 Human SwissProt: Q96T52 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
线粒体内膜蛋白酶样IMP2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 泛素
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid