白细胞介素增强子结合因子2抗体
规格：1mg/1ml
英文名： ILF2
别名： HGNC:6037; ILF 2; ilf2; ILF2_HUMAN; Interleukin enhancer binding factor 2; Interleukin enhancer binding factor 2, 45kDa; Interleukin enhancer-binding factor 2; MGC8391; NF 45; NF45; Nuclear factor of
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ILF2
交叉反应：Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
细胞定位：细胞核
白细胞介素增强子结合因子2抗体产品介绍：background: The protein encoded by this gene is the 45 kDa component of nuclear factor of activated T-cells (NFAT), a heterodimer of 45 kDa and 90 kDa proteins. NFAT is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The complex has been shown to repair DNA breaks by nonhomologous end joining and can also negatively regulate the microRNA processing pathway. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Jun 2012] Function: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2白细胞介素增强子结合因子2抗体 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Subcellular Location: Nucleus > nucleolus. Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated白细胞介素增强子结合因子2抗体 mRNAs. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 DZF domain. Gene ID: 3608 Database links: Entrez Gene: 3608 Human Entrez Gene: 67781 Mouse Entrez Gene: 310612 Rat Omim: 603181 Human SwissProt: Q12905 Human SwissProt: Q9CXY6 Mouse SwissProt: Q7TP98 Rat Unigene: 75117 Human Unigene: 227258 Mouse Unigene: 137428 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
白细胞介素增强子结合因子2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid