谷氨酰胺转胺酶5抗体
规格：1mg/1ml
英文名： Transglutaminase 5
别名： Protein glutamine gamma glutamyltransferase 5; Protein-glutamine gamma-glutamyltransferase 5; TG(X); TGase 5; TGase X; TGase-5; TGase5; TGM5; TGM5_HUMAN; TGMX; TGX; Transglutaminase X; Transglutaminas
分子量： 81kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Transglu
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞膜
谷氨酰胺转胺酶5抗体产品介绍：background: This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009] Function: Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes. Subcellular Location: Cytoplasm. Associated with intermediate filaments. Tissue Specificity: Expressed in foreskin keratinocytes.谷氨酰胺转胺酶5抗体 DISEASE: Defects in TGM5 are a cause of peeling skin syndrome type A (APSS) [MIM:609796]. A non-inflammatory form of peeling skin syndrome, a genodermatosis characterized by the continuous shedding of the outer layers of the epidermis. In APSS patients, skin peeling is strictly limited to the dorsa of the hands and feet, and it is accompanied by accompanied by painless erythema and spontaneous non-scarring healing. Ultrastructural and histological analysis shows a level of blistering high in the epidermis at the stratum granulosum-stratum corneum junction.谷氨酰胺转胺酶5抗体 Similarity: Belongs to the transglutaminase superfamily. Transglutaminase family. Gene ID: 9333 Database links: Entrez Gene: 9333 Human Entrez Gene: 74176 Mouse Entrez Gene: 691929 Rat Omim: 603805 Human SwissProt: O43548 Human SwissProt: Q3V1F9 Mouse SwissProt: Q9D7I9 Mouse Unigene: 129719 Human Unigene: 20187 Mouse Unigene: 198646 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氨酰胺转胺酶5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 结合蛋白 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid