谷氨酰胺转胺酶4抗体
规格：1mg/1ml
英文名： Transglutaminase 4
别名： Dorsal prostate transglutaminase; Dorsal protein 1; Dp1; Fibrinoligase; hTGP; Prostate specific transglutaminase; Prostate transglutaminase; Prostate-specific transglutaminase; Protein glutamine gamma
分子量： 77kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Transglu
交叉反应：Human,
细胞定位：
谷氨酰胺转胺酶4抗体产品介绍：background: Terminally differentiating mammalian epidermal cells acquire an insoluble, 10 to 20 nm thick protein deposit on the intracellular surface of the plasma membrane known as the cross-linked cell envelope (CE). The CE is a component of the epidermis that is generated through formation of disulfide bonds and gamma-glutamyl-lysine isodipeptide bonds, which are formed by the action of transglutaminases (TGases). TGases are intercellularly localizing, Ca2+-dependent enzymes, which catalyze the formation of isopeptide bonds by transferring an amine on to glutaminyl residues, thereby cross-linking glutamine residues and lysine residues in substrate proteins. 谷氨酰胺转胺酶4抗体TGases influence numerous biological processes including blood coagulation, epidermal differentiation, seminal fluid coagulation, fertilization, cell differentiation and apoptosis. TGase4, also known as TGM4, TGP or hTGP, is a typical TGase that is specifically expressed in prostate tissue. Function: Associated with the mammalian reproductive process. Catalyzes the cross-linking of proteins and the conjugation 谷氨酰胺转胺酶4抗体of polyamines to specific proteins in the seminal tract. Tissue Specificity: Prostate. Similarity: Belongs to the transglutaminase superfamily. Transglutaminase family. Gene ID: 7047 Database links: Entrez Gene: 7047 Human Omim: 600585 Human SwissProt: P49221 Human Unigene: 438265 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
谷氨酰胺转胺酶4抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid