相关易位膜蛋白2抗体
规格:1mg/1ml
英文名: TRAM2
别名: C330003D03Rik; KIAA0057; MGC25725; OTTHUMP00000016607; TRAM like protein; Tram2; TRAM2_HUMAN; Translocating chain associating membrane protein 2; Translocating chain-associated membrane protein 2; Tra
分子量: 43kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human TRAM2
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位:细胞膜
相关易位膜蛋白2抗体产品介绍:background: TRAM2 is a component of the translocon, a gated macromolecular channel that controls the posttranslational processing of nascent secretory and membrane proteins at the endoplasmic reticulum (ER) membrane.[supplied by OMIM, Jul 2004] Function: Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+)相关易位膜蛋白2抗体 concentration may be necessary for the function of molecular chaperones involved in collagen folding. Subcellular Location: Membrane. Similarity: Belongs to the TRAM family. Contains 1 TLC (TRAM/LAG1/CLN8) domain. Gene ID: 9697 Database links: Entrez Gene: 9697 Human Entrez Gene: 617287 Cow Entrez Gene: 474936 Dog Entrez Gene: 100730382 Guinea pig Entrez Gene: 100069225 Horse Entrez Gene: 相关易位膜蛋白2抗体170829 Mouse Entrez Gene: 100157796 Pig Entrez Gene: 301296 Rat Entrez Gene: 406344 Zebrafish Omim: 608485 Human SwissProt: Q15035 Human SwissProt: Q924Z5 Mouse Unigene: 520182 Human Unigene: 185680 Mouse Unigene: 273241 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
相关易位膜蛋白2抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 跨膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid