肿瘤坏死因子受体相关因子5抗体
规格：1mg/1ml
英文名： TRAF5
别名： RING finger protein 84; RING finger protein 84; RNF84; TNF receptor associated factor 5; TNF receptor-associated factor 5; TRAF 5; Traf5; TRAF5_HUMAN.
分子量： 64kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human TRAF5
交叉反应：Human, Pig, Horse,
细胞定位：细胞浆
肿瘤坏死因子受体相关因子5抗体产品介绍：background: The scaffold protein encoded by this gene is a member of the tumor necrosis factor receptor-associated factor (TRAF) protein family and contains a meprin and TRAF homology (MATH) domain, a RING-type zinc finger, and two TRAF-type zinc fingers. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. This protein is one of the components of a multiple protein complex which binds to tumor necrosis factor (TNF) receptor cytoplasmic domains and mediates TNF-induced activation. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]肿瘤坏死因子受体相关因子5抗体 Function: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Subcellular Location: Cytoplasm. Tissue Specificity: Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood. Similarity: Belongs to the TNF receptor-associated factor family. A subfamily. Contains 1 MATH domain. 肿瘤坏死因子受体相关因子5抗体Contains 1 RING-type zinc finger. Contains 2 TRAF-type zinc fingers. Gene ID: 7188 Database links: Entrez Gene: 7188 Human Entrez Gene: 507234 Cow Entrez Gene: 480019 Dog Omim: 602356 Human SwissProt: O00463 Human Unigene: 523930 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肿瘤坏死因子受体相关因子5抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid