类固醇脱氢酶样蛋白1抗体
规格:1mg/1ml
英文名: HSDL1
别名: hsdl1; Hydroxysteroid dehydrogenase like protein 1; HSDL1_HUMAN; steroid dehydrogenase like.
分子量: 37kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSDL1
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Sheep,
细胞定位:
类固醇脱氢酶样蛋白1抗体产品介绍:background: HSDL1 is a 330 amino acid protein that belongs to the short-chain dehydrogenases/reductases (SDR) family and 17-beta-HSD 3 subfamily. Localizing to the mitochondrion, HSDL1 is highly expressed in testis and ovary, with lower levels of expression found in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. HSDL1 interacts with DUSP24 and is encoded by a gene that maps to human chromosome 16q23.3 and mouse chromosome 8 E1. Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA, and is associated with a variety of genetic disorders. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16 through the CREBBP gene, which encodes a类固醇脱氢酶样蛋白1抗体critical CREB binding protein. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. Function: Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. Subcellular Location: Mitochondrion. Tissue Specificity: Highly expressed in testis and ovary. Also detected in thyroid, spinal cord, adrenal gland, heart, placenta, skeletal muscle, small intestine, colon, spleen, prostate and pancreas. 类固醇脱氢酶样蛋白1抗体Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily. Gene ID: 83693 Database links: Entrez Gene: 83693 Human Entrez Gene: 72552 Mouse Entrez Gene: 361418 Rat SwissProt: Q3SXM5 Human SwissProt: Q8BTX9 Mouse SwissProt: Q4V8B7 Rat Unigene: 555992 Human Unigene: 36756 Mouse Unigene: 199069 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
类固醇脱氢酶样蛋白1抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 新陈代谢
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid