17β羟类固醇脱氢酶7抗体
规格:1mg/1ml
英文名: HSD17B7
别名: 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto
分子量: 33kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSD17B7
交叉反应:Human,
细胞定位:细胞膜
17β羟类固醇脱氢酶7抗体产品介绍:background: HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).[supplied by OMIM, May 2010] Function: Responsible for the reduction of the keto group on the C-3 of sterols. Subcellular Location: Cell membrane. Tissue Specificity: Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all 17β羟类固醇脱氢酶7抗体other tissues tested. Isoform 3 is expressed in eye ciliary epithelial cells and neuroendocrine cells. Post-translational modifications: Phosphorylated. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. ERG27 subfamily. Gene ID: 5147817β羟类固醇脱氢酶7抗体 Database links: Entrez Gene: 51478 Human Entrez Gene: 15490 Mouse Entrez Gene: 29540 Rat Omim: 606756 Human SwissProt: P56937 Human SwissProt: O88736 Mouse SwissProt: Q62904 Rat Unigene: 492925 Human Unigene: 12882 Mouse Unigene: 7040 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
17β羟类固醇脱氢酶7抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:肿瘤 细胞生物 信号转导 新陈代谢 细胞膜蛋白
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid