17β羟类固醇脱氢酶14/17β-HSD14抗体
规格:1mg/1ml
英文名: HSD17B14
别名: 17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; DHRS10; DHB14_HUMAN; Retinal short chain dehydrogenase/reductase 3;
分子量: 28kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human HSD17B14
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:细胞浆
17β羟类固醇脱氢酶14/17β-HSD14抗体产品介绍:background: 17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17 position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007 [PubMed 17067289]).[supplied by OMIM, Jun 2009] Function: HSD17B14 belongs to the short-chain dehydrogenases/reductases (SDR) family. It has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity and converts oestradiol to oestrone. 17β羟类固醇脱氢酶14/17β-HSD14抗体The physiological substrate is not known. HSD17B14 acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). It is highly expressed in brain, placenta, liver and kidney. Subunit: Homotetramer. Subcellular Location: Cytoplasmic 17β羟类固醇脱氢酶14/17β-HSD14抗体Tissue Specificity: Highly expressed in brain, placenta, liver and kidney. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Gene ID: 51171 Database links: Entrez Gene: 51171 Human Omim: 612832 Human SwissProt: Q9BPX1 Human Unigene: 18788 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
17β羟类固醇脱氢酶14/17β-HSD14抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 生长因子和**
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid