HEY1蛋白抗体
规格：1mg/1ml
英文名： HEY1
别名： Basic helix loop helix protein OAF1; bHLHb31; Cardiovascular helix loop helix factor 2; Cardiovascular helix loop-helix factor 2; Cardiovascular helix-loop-helix factor 2; CHF 2; CHF-2; CHF2; Class B
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human HEY1
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：细胞核
HEY1蛋白抗体产品介绍：background: This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008] Function: Downstream HEY1蛋白抗体effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. Subcellular Location: Nucleus. Tissue Specificity: Expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs.HEY1蛋白抗体 Similarity: Belongs to the HEY family. Contains 1 basic helix-loop-helix (bHLH) domain. Contains 1 Orange domain. Gene ID: 23462 Database links: Entrez Gene: 23462 Human Entrez Gene: 403420 Dog Entrez Gene: 15213 Mouse Entrez Gene: 155437 Rat Omim: 602953 Human SwissProt: Q9TSZ2 Dog SwissProt: Q9Y5J3 Human SwissProt: Q9WV93 Mouse Unigene: 234434 Human Unigene: 29581 Mouse Unigene: 98202 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
HEY1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：心血管 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid