血红蛋白γ2抗体
规格：1mg/1ml
英文名： Hemoglobin subunit gamma 2
别名： Abnormal hemoglobin; FLJ76540; G gamma globin; Gamma 2 globin; Gamma-2-globin; Hb F Ggamma; HBG 2; HBG2; HBG2_HUMAN; Hemoglobin gamma 2 chain; Hemoglobin gamma G; Hemoglobin gamma G chain; Hemoglobin
分子量： 16kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Hemoglob
交叉反应：Human,
细胞定位：
血红蛋白γ2抗体产品介绍：background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by ***** hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into *****hood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] Function: Gamma chains make up the fetal hemoglobin F, in combination with alpha chains. Subcellular Location: Belongs to血红蛋白γ2抗体 the globin family. Tissue Specificity: Red blood cells. Post-translational modifications: Acetylation of Gly-2 converts Hb F to the minor Hb F1. DISEASE: Defects in HBG2 are the cause of cyanosis transient neonatal (TNCY) [MIM:613977]. TNCY is a disorder characterized by cyanosis in the fetus and neonate, due to a defect in the fetal hemoglobin chain which has reduced affinity for oxygen. Some patients develop anemia 血红蛋白γ2抗体ths of age or earlier, as the ***** beta-globin chain is produced and replaces the fetal gamma-globin chain. Similarity: Belongs to the globin family. Gene ID: 3048 Database links: Entrez Gene: 3048 Human Omim: 142250 Human SwissProt: P69892 Human Unigene: 302145 Human Unigene: 712539 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
血红蛋白γ2抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid