ZNHIT3蛋白抗体
规格：1mg/1ml
英文名： ZNHIT3
别名： HNF 4a coactivator; Thyroid hormone receptor interactor 3; Thyroid receptor interacting protein 3; TR interacting protein 3; TRIP 3; ZNHI3_HUMAN; TRIP3; Zinc finger HIT domain containing protein 3; Zi
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZNHIT3
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：
ZNHIT3蛋白抗体产品介绍：background: ZNHIT3 is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR?mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4? and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved inZNHIT3蛋白抗体 DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Function: ZNHIT3 functions as a transcriptional coactivator and contains 1 HIT type zinc finger. Subunit: Thyroid receptor interacting proteins (TRIPs) specifically interact with the ligand binding domain of the thyroid receptor (TR). Requires theZNHIT3蛋白抗体 presence of thyroid hormone for its interaction. Similarity: Contains 1 HIT-type zinc finger. Gene ID: 9326 Database links: Entrez Gene: 9326 Human Omim: 604500 Human SwissProt: Q15649 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZNHIT3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. T
来源： Rabbit
外观： Lyophilized or Liquid