通用转录因子ⅡA亚基1/TFIIA-α抗体
规格：1mg/1ml
英文名： GTF2A1 alpha
别名： General transcription factor IIA subunit 1; General transcription factor IIA1; Glucose regulated protein 58kD pseudogene; gtf2a1; TF2A1; TF2AA_HUMAN; TFIIA 42; TFIIA alpha p55; TFIIA alpha p55, isofor
分子量： 35/42kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GTF2A1 a
交叉反应：Human, Mouse, Rat, Rabbit, Sheep,
细胞定位：
通用转录因子ⅡA亚基1/TFIIA-α抗体产品介绍：background: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and several general initiation factors (summarized by DeJong and Roeder, 1993 [PubMed 8224848]). One of these factors is TFIIA, which when purified from HeLa extracts consists of 35-, 19-, and 12-kD subunits.[supplied by OMIM, Jul 2010] Function: TFIIA is a component of the transcription machinery of RNA polymerase II and plays an通用转录因子ⅡA亚基1/TFIIA-α抗体 important role in transcriptional activation. TFIIA in a complex with TBP mediates transcriptional activity. Subcellular Location: Nucleus. Post-translational modifications: The alpha and beta subunits are postranslationally produced from the precursor form by TASP1. The cleavage promotes proteasomal degradation. Similarity: Belongs to the TFIIA subunit 1 family. Gene ID: 2957 Database links: Entrez 通用转录因子ⅡA亚基1/TFIIA-α抗体Gene: 2957 Human Entrez Gene: 83602 Mouse Entrez Gene: 83830 Rat Omim: 600520 Human SwissProt: P52655 Human SwissProt: Q99PM3 Mouse SwissProt: O08949 Rat Unigene: 592334 Human Unigene: 275728 Mouse Unigene: 432242 Mouse Unigene: 44436 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
通用转录因子ⅡA亚基1/TFIIA-α抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid