ZRSR2蛋白抗体
规格:1mg/1ml
英文名: ZRSR2
别名: CCCH type zinc finger, RNA binding motif and serine/arginine rich protein 2; MGC142014; U2AFM_HUMAN; MGC142040; Renal carcinoma antigen NY REN 20; U2 small nuclear ribonucleoprotein auxiliary factor 3
分子量: 58kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human ZRSR2
交叉反应:Human,
细胞定位:细胞核
ZRSR2蛋白抗体产品介绍:background: This gene encodes an essential splicing factor. The encoded protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. [provided by RefSeq, Jul 2008] Function: ZRSR2 is an essential splicing factor. The protein associates with the U2 auxiliary factor heterodimer, which is required for the recognition of a functional 3' splice site in pre-mRNA splicing, and may play a role in network interactions during spliceosome assembly. This gene encodes U2AF small subunit related protein 2 which is an essential splicing factor. This protein is associated with the U2AF heterodimer composed of a large and a small subunit. It specifically interacts with the large subunit through an U2AF small subunit homologous region, and with SR proteins through its RS domain. This protein and U2AF small subunit are not functionally ZRSR2蛋白抗体redundant. Subunit: Component of the U11/U12 snRNPs that are part of the U12-type spliceosome. Interacts (via RS domain) with SRSF1 and SRSF2. Interacts with U2AF2/U2AF65. Subcellular Location: Nuclear Tissue Specificity: Widely expressed.ZRSR2蛋白抗体 Post-translational modifications: Phosphorylated in the RS domain by SRPK1. Similarity: Contains 2 C3H1-type zinc fingers. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 8233 Database links: Entrez Gene: 8233 Human Entrez Gene: 22184 Mouse Entrez Gene: 302670 Rat Omim: 300028 Human SwissProt: Q15696 Human SwissProt: Q62377 Mouse Unigene: 171909 Human Unigene: 426178 Mouse Unigene: 26786 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ZRSR2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid