锌指蛋白ZXDC抗体
规格：1mg/1ml
英文名： ZXDC
别名： SERH2790; UNQ2790; Zinc finger protein ZXDC; ZXD family zinc finger C; ZXD like zinc finger protein; ZXD-like zinc finger protein; Zxdc; ZXDC_HUMAN; ZXDL.
分子量： 89kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ZXDC
交叉反应：Human, Mouse, Rat, Cow, Rabbit, Sheep,
细胞定位：细胞核
锌指蛋白ZXDC抗体产品介绍：background: Zinc finger X-linked duplicated family member C (ZXDC) is an 858 amino acid protein belonging to the ZDX family. Localized to the nucleus, ZDXC is expressed at high levels in heart, kidney, liver and testis, with lower levels of expression in lung, muscle, placenta, small intestine and spleen. ZDXC, with ZDXA, forms a complex that binds to the class II trans-activator (CIITA). CIITA, like the X1-binding regulatory factor X (RFX) complex and the nuclear factor Y (NFY) complex, is a transcriptional co-factor that is necessary, but not sufficient, for major histocompatibility complex (MHC) class II gene transcription. ZXDC, by regulating CIITA function, activates the transcription of MHC genes. Function: Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes. Subcellular 锌指蛋白ZXDC抗体Location: Nucleus. Tissue Specificity: Expressed at high levels in heart, kidney, liver and testis, at moderate levels in brain and stomach, and at low levels in lung, muscle, placenta, small intestine and spleen. Similarity: Belongs to the ZXD family. Contains 10 C2H2-type锌指蛋白ZXDC抗体 zinc fingers. Gene ID: 79364 Database links: Entrez Gene: 79364 Human Entrez Gene: 80292 Mouse Entrez Gene: 362399 Rat SwissProt: Q2QGD7 Human SwissProt: Q8C8V1 Mouse Unigene: 440049 Human Unigene: 711046 Human Unigene: 100116 Mouse Unigene: 473652 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
锌指蛋白ZXDC抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 转录调节因子 锌指蛋白 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid