GW182蛋白抗体
规格：1mg/1ml
英文名： GW182
别名： CAG repeat protein 26; CAGH26; DKFZp666E117; EDIE; EMSY interactor protein; FLJ22043; Glycine tryptophan protein of 182 kDa; Glycine-tryptophan protein of 182 kDa; GW1; GW182; GW182 autoantigen; Hypot
分子量： 210kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GW182
交叉反应：Human, Mouse, Rat,
细胞定位：细胞浆
GW182蛋白抗体产品介绍：background: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008] Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. Subcellular Location: Cytoplasm > GW182蛋白抗体P-body. Mammalian P-bodies are also known as GW bodies. Tissue Specificity: Ubiquitous. Similarity: Belongs to the GW182 family. Contains 1 RRM (RNA recognition motif) domain. Gene ID: 27327 Database links: Entrez Gene: 27327 Human Entrez Gene: 233833 GW182蛋白抗体Mouse Entrez Gene: 308971 Rat Omim: 610739 Human SwissProt: Q8NDV7 Human SwissProt: Q3UHK8 Mouse Unigene: 407740 Human Unigene: 655057 Human Unigene: 102305 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GW182蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid