ERAL1蛋白抗体
规格：1mg/1ml
英文名： ERAL1/GTP binding protein era homolog
别名： CEGA; Conserved ERA like GTPase; Conserved ERA-like GTPase; ERA; Era (E. coli G protein homolog) like 1; Era G protein like 1 (E. coli); Era G protein like 1; ERA W; ERA-like protein 1; ERA-W; Eral1;
分子量： 43kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ERAL1/GT
交叉反应：Human, Mouse, Rat, Pig, Cow, Sheep,
细胞定位：
ERAL1蛋白抗体产品介绍：background: CEGA is a 437 amino acid human homolog of Era. Functioning as a probable GTP-binding protein, ERAL1 contains the same structural domains as its yeast counterpart, namely a conserved BoxA sequence, a C-terminal KH domain and an N-terminal GTP-binding domain. Due to the high level of structural similarity with Era, ERAL1 may participate in cell cycle events, including cellular proliferation and cell division. ERAL1 contains one KH type-2 domain and is expressed as two isoforms, designated HERA-A and HERA-B, which are produced due to alternative splicing events. Function: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as aERAL1蛋白抗体 chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly. Subcellular Location: Mitochondrion matrix. Mitochondrion inner membrane. Localizes on the matrix side on the mitochondrial inner membrane.ERAL1蛋白抗体 Similarity: Belongs to the Era/MnmE GTP-binding protein family. Era subfamily. Contains 1 G (guanine nucleotide-binding) domain. Contains 1 KH type-2 domain. Gene ID: 26284 Database links: Entrez Gene: 26284 Human Entrez Gene: 57837 Mouse Entrez Gene: 363646 Rat Omim: 607435 Human SwissProt: O75616 Human SwissProt: Q9CZU4 Mouse SwissProt: Q5EBA0 Rat Unigene: 3426 Human Unigene: 21096 Mouse Unigene: 99076 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
ERAL1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid