通用转录因子2H亚基3/TTFIIH p34抗体
规格:1mg/1ml
英文名: GTF2H3
别名: Basic transcription factor 2 34 kDa subunit; BTF2; BTF2 p34; General transcription factor IIH polypeptide 3; General transcription factor IIH subunit 3; general transcription factor IIH, polypeptide 3
分子量: 34kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GTF2H3
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Chinese Hamster
细胞定位:细胞核
通用转录因子2H亚基3/TTFIIH p34抗体产品介绍:background: This gene encodes a member of the TFB4 family. The encoded protein is a subunit of the core-TFIIH basal transcription factor and localizes to the nucleus. The encoded protein is involved in RNA transcription by RNA polymerase II and nucleotide excision repair and associates with the Cdk-activating kinase complex. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 14. [provided by RefSeq, Dec 2012] Function: Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by 通用转录因子2H亚基3/TTFIIH p34抗体RNA polymerase II. Anchors XPB. Subcellular Location: Nucleus. Similarity: Belongs to the TFB4 family. Gene ID: 2967 Database links: Entrez Gene: 2967 Human Entrez Gene: 511896 Cow Entrez Gene: 100059174 Horse Entrez Gene: 通用转录因子2H亚基3/TTFIIH p34抗体209357 Mouse Entrez Gene: 288651 Rat Omim: 601750 Human SwissProt: Q05B56 Cow SwissProt: Q13889 Human SwissProt: Q8VD76 Mouse SwissProt: Q561R7 Rat Unigene: 355348 Human Unigene: 185467 Mouse Unigene: 203542 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
通用转录因子2H亚基3/TTFIIH p34抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 转录调节因子 表观遗传学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid