G蛋白偶联受体112抗体
规格:1mg/1ml
英文名: GPR112
别名: GP112_HUMAN; GPR112; PGR17; Probable G-protein coupled receptor 112; RP1-299I16.
分子量: 330kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GPR112
交叉反应:Human, Mouse,
细胞定位:细胞膜
G蛋白偶联受体112抗体产品介绍:background: This gene encodes a G-protein coupled receptor belonging to a large family of diverse integral membrane proteins that participate in various physiological functions. Members of this superfamily are characterized by a signature 7-transmembrane domain motif. The ligand for this family member is unknown, and it is therefore an orphan receptorG蛋白偶联受体112抗体. This receptor is known to be expressed in normal enterochromaffin cells and in gastrointestinal neuroendocrine carcinoma cells, and it is therefore considered to be a novel biomarker or target for immunotherapy. [provided by RefSeq, May 2010] Function: Orphan receptor. Subcellular Location: Cell membrane. Tissue Specificity: Detected in fetal retina. Highly expressed in normal enterochromaffin cells and in neuroendocrine carcinoma. Detected in normal liver; highly expressed in primary liver carcinoma. Similarity: Belongs to the G-protein coupled receptor G蛋白偶联受体112抗体2 family. LN-TM7 subfamily. Contains 1 GPS domain. Gene ID: 139378 Database links: Entrez Gene: 139378 Human SwissProt: Q8IZF6 Human Unigene: 381354 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体112抗体产品应用:ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:信号转导 G蛋白偶联受体 G蛋白信号
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid