G蛋白偶联受体167抗体
规格：1mg/1ml
英文名： GPCR MRGE/GPCR GPR167
别名： G protein coupled receptor 167; G-protein coupled receptor 167; GPR167; Mas related G protein coupled MRGE; MAS related GPR member E; Mas-related G-protein coupled receptor member E; MRGE; MRGPRE; MRG
分子量： 34kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GPCR MRG
交叉反应：Human,
细胞定位：细胞膜
G蛋白偶联受体167抗体产品介绍：background: MRGE is a 311 amino acid multi-pass membrane protein that acts as an orphan receptor and is though to influence nociceptor function. A member of the G-protein coupled receptor 1 family and MAS subfamily, MRGE is encoded by a gene that maps to human chromosome 11p15.4 and mouse chromosome 7 F5. Chromosome 11 comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. G蛋白偶联受体167抗体Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes. Function: Orphan receptor. May regulate nociceptor function G蛋白偶联受体167抗体and/or development, including the sensation or modulation of pain. Subcellular Location: Cell membrane. Similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. Gene ID: 116534 Database links: Entrez Gene: 116534 Human Entrez Gene: 244238 Mouse Entrez Gene: 404660 Rat Omim: 607232 Human SwissProt: Q86SM8 Human SwissProt: Q91ZB7 Mouse SwissProt: Q7TN40 Rat Unigene: 706565 Human Unigene: 183561 Mouse Unigene: 189891 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
G蛋白偶联受体167抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：信号转导 细胞凋亡 G蛋白偶联受体 G蛋白信号
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid