GALNTL6蛋白抗体
规格:1mg/1ml
英文名: GALNTL6
别名: EC 2.4.1.41; GalNAc transferase 17; GalNAc-T17; GALNACT20; GALNTL6; GaNTase 17; GLTL6_HUMAN; MGC44629; OTTHUMP00000219021; OTTHUMP00000219023; Polypeptide GalNAc transferase 17; Polypeptide N-acetylga
分子量: 70kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GALNTL6
交叉反应:Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
细胞定位:
GALNTL6蛋白抗体产品介绍:background: GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors. Function: GalNAc-T17 is a 601 amino acid single-pass type II membrane protein that is a member of the glycosyltransferase 2 family GALNTL6蛋白抗体and GalNAc-T subfamily. Localized to the Golgi apparatus and contains a ricin B-type lectin domain, GalNAc-T17 catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. GalNAc-T17 contains two conserved domains, an N-terminal domain (domain A, also called GT1 motif), which is likely involved in manganese coordination and substrate binding and a C-terminal domain (domain B, also called Gal/GalNAc-T motif), which is likely involved in catalytic reaction and UDP-Gal binding. GalNAc-T17 exists as two alternatively spliced isoforms and utilizes manganese and calcium as cofactors Subcellular Location: GALNTL6蛋白抗体Golgi apparatus membrane. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 442117 Database links: Entrez Gene: 442117 Human Entrez Gene: 615819 Cow Entrez Gene: 486063 Dog Entrez Gene: 270049 Mouse Entrez Gene: 361142 Rat Omim: 615138 Human SwissProt: Q49A17 Human Unigene: 386236 Human Unigene: 236368 Mouse Unigene: 214629 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GALNTL6蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学 信号转导
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid