GalNAc-T9蛋白抗体
规格：1mg/1ml
英文名： GALNT9
别名： GalNAc T9; GalNAc transferase 9; GalNAc-T9; GALNT9; GALT9_HUMAN; Polypeptide GalNAc transferase 9; Polypeptide N acetylgalactosaminyltransferase 9; Polypeptide N-acetylgalactosaminyltransferase 9; pp
分子量： 68kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNT9
交叉反应：Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Zebrafish, Sheep, Danio
细胞定位：
GalNAc-T9蛋白抗体产品介绍：background: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this geneGalNAc-T9蛋白抗体. [provided by RefSeq, Jul 2008] Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe,GalNAc-T9蛋白抗体 putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 50614 Database links: Entrez Gene: 50614 Human Entrez Gene: 504951 Cow Entrez Gene: 486224 Dog Entrez Gene: 100718062 Guinea pig Entrez Gene: 231605 Mouse Entrez Gene: 100156842 Pig Entrez Gene: 304571 Rat Entrez Gene: 797549 Zebrafish Omim: 606251 Human SwissProt: Q9HCQ5 Human Unigene: 301062 Human Unigene: 658249 Human Unigene: 275748 Mouse Unigene: 105079 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-T9蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学 信号转导 新陈代谢
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid