GalNAc-TL1蛋白抗体
规格：1mg/1ml
英文名： GALNTL1
别名： GalNAc T like protein 1; GALNACT16; GALNT16; GLT16_HUMAN; Human GalNAc T16 DNA sequence; KIAA1130; mpp-GalNAc-T16; N acetylgalactosaminyltransferase like protein 1; Polypeptide GalNAc transferase like
分子量： 63kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNTL1
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：
GalNAc-TL1蛋白抗体产品介绍：background: The UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes are substrate-specific proteins that catalyze the transfer of GalNAc (N-acetylgalactosaminyl) to serine and threonine residues onto various proteins, thereby initiating mucin-type O-linked glycosylation in the Golgi apparatus. GalNAc-TL1 (UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1), also known as GALNT16, is a 588 amino acid single-pass type GalNAc-TL1蛋白抗体II membrane protein belonging to the glycosyltransferase 2 family, which localizes to the Golgi apparatus. GalNAc-TL1 utilizes manganese and calcium as cofactors, and catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, which involves the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Containing one ricin B-type lectin domain, GalNAc-TL1 exists as two alternatively spliced isoforms. Function: GALNTL1 belongs to the glycosyltransferase 2 family, GalNAc-T subfamily. It contains 1 ricin B type GalNAc-TL1蛋白抗体lectin domain. GALNTL1 may catalyze the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Subcellular Location: Golgi apparatus membrane; Single pass type II membrane protein Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 57452 Database links: Entrez Gene: 57452 Human Entrez Gene: 108760 Mouse SwissProt: Q8N428 Human SwissProt: Q9JJ61 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-TL1蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid