GalNAc-T6蛋白抗体
规格：1mg/1ml
英文名： GALNT6
别名： GALNAC T6; GalNAc transferase 6; GalNAc-T6; GalNAcT6; GALNT 6; GALNT6; GALT6_HUMAN; Polypeptide GalNAc transferase 6; Polypeptide N acetylgalactosaminyltransferase 6; Polypeptide N-acetylgalactosaminy
分子量： 71kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human GALNT6
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：
GalNAc-T6蛋白抗体产品介绍：background: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetalGalNAc-T6蛋白抗体 fibronectin. [provided by RefSeq, Jul 2008] Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. May participate in synthesis of oncofetal fibronectin. Has activity toward Muc1a, Muc2, EA2 and fibronectin peptides. Subcellular Location: Golgi apparatus membrane. Tissue Specificity: Expressed in placenta and trachea. Weakly expressed in brain and pancreas. Expressed in fibroblast. Weakly or not expressed in lung, liver, muscle, kidney, spleen, thymusGalNAc-T6蛋白抗体, prostate, testis, ovary, intestine, colon, leukocyte, stomach, thyroid, spinal cord, lymph node, trachea, adrenal gland and bone marrow. Similarity: Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 11226 Database links: Entrez Gene: 11226 Human Entrez Gene: 207839 Mouse Entrez Gene: 100361647 Rat SwissProt: Q5EA41 Cow SwissProt: Q8NCL4 Human SwissProt: Q8C7U7 Mouse Unigene: 505575 Human Unigene: 22969 Mouse Unigene: 104292 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GalNAc-T6蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 细胞生物 细胞类型标志物
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid