GALNT2蛋白抗体
规格:1mg/1ml
英文名: GALNT2
别名: GalNAc T2; GalNAc-T2; Galnt2; GALT2_HUMAN; GaNTase 2; Polypeptide GalNAc transferase 2; Polypeptide N acetylgalactosaminyltransferase 2; Polypeptide N acetylgalactosaminyltransferase 2 soluble form; P
分子量: 65kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human GALNT2
交叉反应:Human, Mouse, Rat,
细胞定位:
GALNT2蛋白抗体产品介绍:background: This gene encodes polypeptide N-acetylgalactosaminyltransferase 2, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation in a cell is regulated by a repertoire of GalNAc-transferases. [provided by RefSeq, Jul 2008] Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad sGALNT2蛋白抗体pectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region. Subcellular Location: Golgi apparatus; Golgi stack membrane. Secreted. Resides preferentially in the trans and medial parts of the Golgi stack. A secreted form also exists. Tissue Specificity: Widely expressed. Similarity: Belongs to the glycosyltransferase 2 family.GALNT2蛋白抗体 GalNAc-T subfamily. Contains 1 ricin B-type lectin domain. Gene ID: 2590 Database links: Entrez Gene: 2590 Human Entrez Gene: 108148 Mouse Entrez Gene: 292090 Rat Omim: 602274 Human SwissProt: Q10471 Human SwissProt: Q6PB93 Mouse Unigene: 654649 Human Unigene: 33808 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
GALNT2蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid