肝肠钙粘连蛋白抗体
规格：1mg/1ml
英文名： LI Cadherin
别名： BILL-cadherin; LI-cadherin; CAD17_HUMAN; Cadherin 16; Cadherin 16, formerly; Cadherin 17; cadherin 17, LI cadherin (liver-intestine); cadherin, liver-intestine; Cadherin-17; CDH16; CDH16, formerly; Cd
分子量： 90kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human LI-cadhe
交叉反应：Human, Mouse, Rat,
细胞定位：
肝肠钙粘连蛋白抗体产品介绍：background: This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript肝肠钙粘连蛋白抗体 variants. Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. LI-cadherin may have a role in the morphological organization of liver and intestine. Involved in intestinal peptide transport. Subcellular Location: Cell membrane; Single-pass 肝肠钙粘连蛋白抗体type I membrane protein (Potential). Tissue Specificity: Expressed in the gastrointestinal tract and pancreatic duct. Not detected in kidney, lung, liver, brain, adrenal gland and skin. Similarity: Contains 7 cadherin domains. Gene ID: 1015 Database links: Entrez Gene: 1015 Human Omim: 603017 Human SwissProt: Q12864 Human Unigene: 591853 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 肝肠钙粘连蛋白是钙粘连蛋白超家族中的特殊一员,在结构上与经典Ⅰ型钙粘连蛋白有所不同而被划分为经典钙粘连蛋白的变异体，主要用于消化道肿瘤方面的研究。
肝肠钙粘连蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid