FOXJ2蛋白抗体
规格：1mg/1ml
英文名： FOXJ2
别名： FHX; Fork head homologous X; Forkhead box J2; Forkhead box protein J2; FOXJ2; FOXJ2_HUMAN.
分子量： 62kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FOXJ2
交叉反应：Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep,
细胞定位：细胞核
FOXJ2蛋白抗体产品介绍：background: FOXJ2, Forkhead box protein J2, is a 574 amino acid protein encoded by the human gene FOXJ2. FOXJ2 is a novel forkhead factor, belonging to the forkhead family, with a dual DNA binding specificity. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in *****s. In the testis, FOXJ2 is expressed from pachytene spermatocytes to round spermatids, but not in spermatogonia. In addition to the germ lineage, only Sertoli cells of the testis showed expression of FOXJ2. In the ovary, only granulosa cells of the follicles express the factor. Neither mature spermatozoa nor oocytes have been found to express FOXJ2. However, both the trophectoderm FOXJ2蛋白抗体(TE) and the inner cell mass (ICM) cell layers of the blastocyst express FOXJ2. Function: Transcriptional activator. Able to bind to two different type of DNA binding sites. Isoform FOXJ2.L behaves as a more potent transactivator than FOXJ2.S. Subcellular Location: Nucleus.FOXJ2蛋白抗体Tissue Specificity: Widely expressed. Post-translational modifications: Phosphorylated upon DNA damage, probably by ATM or ATR. Similarity: Contains 1 fork-head DNA-binding domain. Gene ID: 55810 Database links: Entrez Gene: 55810 Human Entrez Gene: 60611 Mouse Entrez Gene: 502886 Rat SwissProt: Q9P0K8 Human SwissProt: Q9ES18 Mouse Unigene: 120844 Human Unigene: 87142 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FOXJ2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 转录调节因子 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid