环指蛋白207抗体
规格:1mg/1ml
英文名: RNF207
别名: FLJ46380; C1orf188; D330010C22Rik; FLJ32096; FLJ46380; FLJ46593; Gm143; Ring finger protein 207; RN207_HUMAN; RNF 207; RNF207; RP23-421E12.8.
分子量: 71kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human RNF207
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位:
环指蛋白207抗体产品介绍:background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1环指蛋白207抗体 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. 环指蛋白207抗体Similarity: Contains 1 B box-type zinc finger. Contains 1 RING-type zinc finger. Gene ID: 388591 Database links: Entrez Gene: 388591 Human Entrez Gene: 433809 Mouse Entrez Gene: 691246 Rat SwissProt: Q6ZRF8 Human SwissProt: Q3V3A7 Mouse Unigene: 716549 Human Unigene: 156205 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
环指蛋白207抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid