8号染色体开放阅读框52抗体
规格：1mg/1ml
英文名： FLJ20530/C8orf52
别名： C8orf52; Chromosome 8 open reading frame 52; FLJ20530; INT8; Integrator complex subunit 8; INTS 8; INT8_HUMAN ； INTS8; KAONASHI protein 1; KAONASHI1; MGC131633.
分子量： 113kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FLJ20530
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
细胞定位：细胞核
8号染色体开放阅读框52抗体产品介绍：background: This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] Function: FLJ20530 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3' 8号染色体开放阅读框52抗体box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Subunit: Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.8号染色体开放阅读框52抗体 Subcellular Location: Nuclear Similarity: Contains 4 TPR repeats. Gene ID: 55656 Database links: Entrez Gene: 55656 Human Entrez Gene: 72656 Mouse Omim: 611351 Human SwissProt: Q75QN2 Human SwissProt: Q80V86 Mouse Unigene: 521693 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
8号染色体开放阅读框52抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid