FKBP1B/FKBP9蛋白抗体
规格：1mg/1ml
英文名： FKBP1B
别名： 12.6 kDa FK506-binding protein; 12.6 kDa FKBP; Calstabin 2; FK506 binding protein 1 like; FK506 binding protein 12.6; FK506 binding protein 1B 12.6 kDa; FK506 binding protein 1B; FK506-binding protein
分子量： 12kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FKBP1B
交叉反应：Human, Mouse, Rat, Cow,
细胞定位：细胞浆
FKBP1B/FKBP9蛋白抗体产品介绍：background: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008] Function: Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle FKBP1B/FKBP9蛋白抗体RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. Subcellular Location: Cytoplasm. Tissue Specificity: Isoform 1 and isoform 2 are Ubiquitous with highest levels in brain and thymus. Similarity: Belongs to the FKBP-type PPIaseFKBP1B/FKBP9蛋白抗体 family. FKBP1 subfamily. Contains 1 PPIase FKBP-type domain. Gene ID: 2281 Database links: Entrez Gene: 2281 Human Entrez Gene: 14226 Mouse Omim: 600620 Human SwissProt: P68106 Human SwissProt: Q9Z2I2 Mouse Unigene: 407482 Human Unigene: 709461 Human Unigene: 20453 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FKBP1B/FKBP9蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 神经生物学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid