Rab11-FIP3蛋白抗体
规格：1mg/1ml
英文名： RFIP3
别名： EF hands containing Rab interacting protein; Eferin; RFIP3_HUMAN; Rab11 family interacting protein 3; RAB11FIP3; RFIP3.
分子量： 82kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FIP3
交叉反应：Human, Mouse, Rat,
细胞定位：细胞核 细胞浆
Rab11-FIP3蛋白抗体产品介绍：background: Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008] Function: FIP3 (RAB11FIP3) is one of many proteins that interact with and regulate Rab GTPases. Forms an heterooligomeric complex with RAB11FIP4. Binds to RAB11A, RAB11B and RAB25. Subunit: Homodimer. Forms a complex with Rab11 (RAB11A or RAB11B) and ARF6. Interacts with RAB11A; the interaction is direct. Interacts with RAB11B,Rab11-FIP3蛋白抗体 RAB25 and RAB11FIP4. Interacts with ARF6; according to PubMed:16148947, it specifically interacts with ARF6 but not ARF5. Interacts with ARF6; according to PubMed:17030804 but not PubMed:16148947. Interacts with RACGAP1/MgcRacGAP; interaction takes place during late stage of cytokinesis and is required for recruitment to the midbody. Interacts with ASAP1 and EXOC7. Subcellular Location: Recycling endosomeRab11-FIP3蛋白抗体 membrane; Peripheral membrane protein. Cytoplasm; cytoskeleton; centrosome. Cleavage furrow. Midbody. Post-translational modifications: Phosphorylated at Ser-102 by CDK1 during metaphase, and dephosphorylated as cells enter telophase. Similarity: Contains 2 EF-hand domains. Contains 1 FIP-RBD domain. Gene ID: 9727 Database links: Entrez Gene: 9727 Human Entrez Gene: 303002 Rat Omim: 608738 Human SwissProt: O75154 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Rab11-FIP3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学 信号转导 表观遗传学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid