FCN1蛋白抗体
规格:1mg/1ml
英文名: FCN1
别名: Collagen/fibrinogen domain containing protein 1; Collagen/fibrinogen domain-containing protein 1; Fcn1; FCN1_HUMAN; FCNM; ficolin (collagen/fibrinogen domain containing) 1; Ficolin 1; Ficolin A; Ficol
分子量: 32kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FCN1
交叉反应:Human, Mouse, Rat,
细胞定位:细胞浆
FCN1蛋白抗体产品介绍:background: The ficolin family of proteins are characterized by the presence of a leader peptide, a short N-terminal segment, followed by a collagen-like region, and a C-terminal fibrinogen-like domain. The collagen-like and the fibrinogen-like domains are also found separately in other proteins such as complement protein C1q, C-type lectins known as collectins, and tenascins. However, all these proteins recognize different targets, and are functionally distinct. Ficolin 1 encoded by FCN1 is predominantly expressed in the peripheral blood leukocytes, and has been postulated to function as a plasma protein with elastin-binding activity. [provided by RefSeq, Jul 2008] Subunit: Involved in FCN1蛋白抗体serum exerting lectin activity. Binds GlcNAc. Subcellular Location: Secreted. Found on the monocyte surface. Tissue Specificity: Peripheral blood leukocytes. Also detected in spleen, lung, and thymus, may be due to the presence of tissue macrophages or trapped blood in FCN1蛋白抗体these tissues. Not detected on lymphocytes and granulocytes. Similarity: Belongs to the ficolin lectin family. Contains 1 collagen-like domain. Contains 1 fibrinogen C-terminal domain. Gene ID: 2219 Database links: Entrez Gene: 2219 Human Entrez Gene: 14133 Mouse Entrez Gene: 83517 Rat Omim: 601252 Human SwissProt: O00602 Human SwissProt: O70165 Mouse SwissProt: Q9WTS8 Rat Unigene: 440898 Human Unigene: 10510 Mouse Unigene: 20051 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FCN1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid