FATE1蛋白抗体
规格:1mg/1ml
英文名: FATE1
别名: Cancer/testis antigen 43; CT43; FATE; FATE1; FATE1_HUMAN; fetal and ***** testis expressed 1; fetal and ***** testis expressed transcript protein; Fetal and ***** testis-expressed transcript protein;
分子量: 21kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human FATE1
交叉反应:Human,
细胞定位:细胞膜
FATE1蛋白抗体产品介绍:background: FATE1 (fetal and ***** testis expressed 1), also known as FATE, CT43 (cancer/testis antigen 43) or BJ-HCC-2, is a cancer/testis antigen found in testis and tumor tissues (specifically hepatocarcinoma cells). Its expression is regulated by SF-1 (Steroidogenic Factor 1) and WT1 (Wilms’ tumor protein), two proteins involved in tumorigenesis, suggesting a role for FATE1 in tumor development. FATE1 is exclusively expressed in testis of the 6-11 week old fetus (around the period of gonadal sex differentiation). At 7FATE1蛋白抗体 weeks, FATE1 is coexpressed with SRY and may play a role in early testicular differentiation. In *****s, although predominantly expressed in testis, FATE1 can also be found in heart, kidney, brain, lung and adrenal gland. Mutations in the gene encoding FATE1 may be contributing factors in male infertility. Subcellular Location: Membrane. Tissue Specificity: Testis-specific in fetus (aged from 6 to 11 weeks). In *****, expressed predominantly inFATE1蛋白抗体 testis, with some expression in lung, heart, kidney, adrenal gland and whole brain. Gene ID: 89885 Database links: Entrez Gene: 89885 Human Omim: 300450 Human SwissProt: Q969F0 Human Unigene: 301960 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FATE1蛋白抗体产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 **学
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid