Fascin 2蛋白抗体
规格：1mg/1ml
英文名： Fascin 2
别名： Fascin homolog 2, actin bundling protein, retinal Strongylocentrotus purpuratus; Fascin Strongylocentrotus purpuratus homolog 2 actin bundling protein, retinal; Fascin-2; FSCN2; FSCN2_HUMAN; Retinal f
分子量： 55kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human Fascin 2
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位：细胞浆
Fascin 2蛋白抗体产品介绍：background: This gene encodes a member of the fascin protein family. Fascins crosslink actin into filamentous bundles within dynamic cell extensions. This family member is proposed to play a role in photoreceptor disk morphogenesis. A mutation in this gene results in one form of autosomal dominant retinitis pigmentosa and macular degeneration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Acts as an actin bundling protein. May play a pivotal role in photoreceptor cell-specific events, such as disk morphogenesis. Subcellular Location: Cytoplasm > cytoskeleton. Cell projection > stereocilium. Tissue Specificity: Localized specifically in the outer and inner segments of the photoreceptor cells in the retina. DISEASE: Defects in FSCN2 are the causeFascin 2蛋白抗体 of retinitis pigmentosa type 30 (RP30) [MIM:607921]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP30 inheritance is autosomal dominant. Similarity: Belongs to the fascin family. Gene ID: 25794 Database links: Fascin 2蛋白抗体Entrez Gene: 25794 Human Entrez Gene: 337926 Cow Entrez Gene: 483362 Dog Entrez Gene: 238021 Mouse Entrez Gene: 303741 Rat Omim: 607643 Human SwissProt: O18728 Cow SwissProt: O14926 Human SwissProt: Q32M02 Mouse Unigene: 118555 Human Unigene: 375010 Mouse Unigene: 481403 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Fascin 2蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 细胞骨架
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid