FAM83H蛋白抗体
规格：1mg/1ml
英文名： FAM83H
别名： AI3; FA83H_HUMAN; Fam83h; Family with sequence similarity 83 member H; Protein FAM83H.
分子量： 127kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM83H
交叉反应：Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
细胞定位：
FAM83H蛋白抗体产品介绍：background: Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated withFAM83H蛋白抗体 Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. The FAM83H gene product has been provisionally designated FAM83H pending further characterization. Function: May play a major role in the structural organization and calcification of developing enamel. Tissue Specificity: Expressed in the tooth follicle. DISEASE: Defects in FAM83H are the cause of amelogenesis imperfecta type 3 (AI3) [MIM:130900].FAM83H蛋白抗体 AI3 is an autosomal dominant hypomineralized form of amelogenesis imperfecta, a defect of enamel formation. AI3 is characterized by enamel of normal thickness, but soft and with cheesy consistency. Enamel is lost from tooth soon after eruption. Similarity: Belongs to the FAM83 family. Gene ID: 286077 Database links: Entrez Gene: 286077 Human Omim: 611927 Human SwissProt: Q6ZRV2 Human Unigene: 67776 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAM83H蛋白抗体产品应用：ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid