FAM58A蛋白抗体
规格：1mg/1ml
英文名： FAM58A
别名： Cyclin-M; Cyclin-related protein FAM58A; FA58A_HUMAN; Fam58a; Family with sequence similarity 58 member A; STAR.
分子量： 28kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human FAM58A
交叉反应：Human, Mouse, Rat, Rabbit,
细胞定位：
产品介绍：background: FAM58A (family with sequence similarity 58, member A) and FAM58B (family with sequence similarity 58, member B) are 248 FAM58A蛋白抗体amino acid and 252 amino acid proteins, respectively, that belong to the cyclin-like FAM58 subfamily. Existing as multiple alternatively spliced isoforms, FAM58A interacts with Sall1 and is thought to play a role in cellular proliferation. Defects in the gene encoding FAM58A are associated with toe syndactyly, telecanthus, and anogenital and renal malformations (STAR syndrome), which is characterized by renal and anogenital malformations. FAM58B, a protein that is related to FAM58A, is expressed in healthy retina and breast tissue, as FAM58A蛋白抗体well as in retinoblastoma and breast cancer cell lines, suggesting a role for FAM58B in tumor transformation and metastasis. Function: May have a role in cell proliferation. DISEASE: Toe syndactyly, telecanthus, and anogenital and renal malformations Similarity: Belongs to the cyclin family. Cyclin-like FAM58 subfamily. Gene ID: 92002 Database links: Entrez Gene: 92002 Human Entrez Gene: 303321 Rat Omim:FAM58A蛋白抗体 300708 Human SwissProt: Q8N1B3 Human SwissProt: Q4QQW5 Rat Unigene: 496943 Human Unigene: 38890 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
FAM58A蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid