磷酸化钠钾ATP酶蛋白a1抗体
规格：1mg/1ml
英文名： phospho-alpha 1 Sodium Potassium ATPase (Tyr260)
别名： alpha 1 Sodium Potassium ATPase (phospho Y260); Na,K-ATPase alpha-1; Na+/K+ ATPase 1; Sodium pump 1; ATP1A4; ATP1AL2; ATP1B; ATP1B1; ATPase Na+/K+ transporting alpha 1 polypeptide; ATPase Na+/K+ trans
分子量： 113kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthesised phosphopeptide derived from human
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
细胞定位：细胞膜
磷酸化钠钾ATP酶蛋白a1抗体产品介绍：background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by磷酸化钠钾ATP酶蛋白a1抗体 RefSeq, May2009]. Function: This is the catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of sodium and potassium ions across the plasma membrane. This action creates the electrochemical gradient of sodium and potassium ions, providing the energy for active transport of various nutrients. Subcellular Location: Cell membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Post-translational modifications: Phosphorylation on Tyr-10 modulates pumping 磷酸化钠钾ATP酶蛋白a1抗体activity. Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIC subfamily. Gene ID: 476 Database links: Entrez Gene: 476 Human Entrez Gene: 11928 Mouse Entrez Gene: 397481 Pig Entrez Gene: 24211 Rat Omim: 182310 Human SwissProt: P05023 Human SwissProt: Q8VDN2 Mouse SwissProt: P06685 Rat Unigene: 371889 Human Unigene: 280103 Mouse Unigene: 217534 Rat Unigene: 2992 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
磷酸化钠钾ATP酶蛋白a1抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 转录调节因子 通道蛋白 糖蛋白 细胞膜蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid