肺表面活性蛋白D抗体
规格：1mg/1ml
英文名： SFTPD
别名： SFTPD surfactant protein D; pulmonary surfactant-associated glycoprotein D; COLEC 7; COLEC7; Collectin7; PSP D; PSPD; Pulmonary surfactant apoprotein; Pulmonary surfactant associated protein D; SFTP 4
分子量： 41kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human SP-D
交叉反应：Human, Mouse, Rat, Dog,
细胞定位：
肺表面活性蛋白D抗体产品介绍：background: Surfactant protein D contributes to the lung's defense against inhaled microorganisms. It's a calcium ion dependent carbohydrate binding protein and is structurally similar to other C type mammalian lectins, such as conglutinin and SPA. It has a molecular size of approximately 37-43kDa in its reduced state, 620kDa in non dissociating conditions. Surfactant protein D enhances the production of oxygen radicals by rat alveolar macrophages and regulates some actions of SPA, which is the most abundant surfactant protein. Surfactant protein D is synthesized and secreted by alveolar epithelial type II cells. Function: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser肺表面活性蛋白D抗体 extent other alpha-glucosyl moieties. Subunit: Oligomeric complex of 4 set of homotrimers. Subcellular Location: Secreted, extracellular space, extracellular matrix. Secreted, extracellular space, surface film. Post-translational modifications: The N-terminus is blocked. Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in 肺表面活性蛋白D抗体vertebrates. Similarity: Belongs to the SFTPD family. Contains 1 C-type lectin domain. Contains 1 collagen-like domain. Gene ID: 6441 Database links: Entrez Gene: 6441 Human Entrez Gene: 20390 Mouse Entrez Gene: 25350 Rat Omim: 178635 Human SwissProt: P35247 Human SwissProt: P50404 Mouse SwissProt: P35248 Rat Unigene: 253495 Human Unigene: 1321 Mouse Unigene: 11348 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肺表面活性蛋白D抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：肿瘤 **学
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid