肠道内富含的Kruppel样因子13
规格:1mg/1ml
英文名: KLF13
别名: Basic transcription element binding protein 3; BTE binding protein 3; BTEB3; C2 H2 zinc finger protein; FKLF 2; FKLF2; Kruppel like factor 13; Novel Sp1 like zinc finger transcription factor; NSLP1; R
分子量: 31kDa
储存液:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型:Polyclonal
亚型:IgG
纯化方法:affinity purified by Protein A
**原:KLH conjugated synthetic peptide derived from human KLF13
交叉反应:Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
细胞定位:
肠道内富含的Kruppel样因子13产品介绍:background: Kruppel-like factor 13 (KLF13) belongs to a family of transcription factors that contain three classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by two cysteines and two histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes. KLF13 appears to be an important component of the transcription network required for heart development and cholesterol homeostasis. Function: Represses transcription by binding to the BTE site, a GC-rich DNA element, in competition with the activator SP1. It also represses transcription by interacting with the肠道内富含的Kruppel样因子13 corepressor Sin3A and HDAC1. Activates RANTES expression in T-cells. Subcellular Location: Nucleus. Tissue Specificity: Ubiquitous. Post-translational modifications: Phosphorylated. Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family.肠道内富含的Kruppel样因子13 Contains 3 C2H2-type zinc fingers. Gene ID: 51621 Database links: Entrez Gene: 51621 Human Entrez Gene: 50794 Mouse Omim: 605328 Human SwissProt: Q9Y2Y9 Human SwissProt: Q9JJZ6 Mouse Unigene: 525752 Human Unigene: 240473 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
肠道内富含的Kruppel样因子13产品应用:WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域:细胞生物 信号转导 转录调节因子
储存条件: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源: Rabbit
外观: Lyophilized or Liquid