肝再生增强因子抗体
规格：1mg/1ml
英文名： ALR
别名： Augmenter of Liver Regeneration; ERV1 homolog; GFER; Growth factor erv1 like; hERV; HERV1; HPO.
分子量： 18kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ALR C-te
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow, Horse,
细胞定位：
肝再生增强因子抗体产品介绍：background: The hepatotrophic factor designated augmenter of liver regeneration (ALR) is thought to be one of the factors responsible for the extraordinary regenerative capacity of mammalian liver. It has also been called hepatic regenerative stimulation substance (HSS). Also known as: augmenter of liver regeneration; ERV1 homolog; GFER; Growth factor erv1 like; hERV; HERV1; HPO. Function: Isoform 1: FAD-dependent sulfhydryl oxidase. Within the mitochondrial intermembrane space, participates in a chain of disulfide exchange reactions with MIA40, that generate disulfide bonds in a number of resident proteins with twin Cx3C and Cx9C motifs. Isoform 2:肝再生增强因子抗体 May act as an autocrine hepatotrophic growth factor promoting liver regeneration. Subcellular Location: Mitochondrion intermembrane space and Cytoplasm. Secreted. Tissue Specificity: Ubiquitously expressed. Highest expression in the testis and liver and low expression in the muscle. DISEASE: Defects in GFER are a cause of mitochondrial progressive myopathy with congenital cataract hearing loss and developmental delay (MPMCHD) [MIM:613076]; also called combined mitochondrial complex deficiency. Similarity: Contains 1 ERV/ALR sulfhydryl oxidase domain. Gene 肝再生增强因子抗体ID: 2671 Database links: Entrez Gene: 2671 Human Entrez Gene: 11692 Mouse Omim: 600924 Human SwissProt: P55789 Human SwissProt: P56213 Mouse Unigene: 726325 Human Unigene: 28124 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. ALR是近年来发现的一种促肝****的细胞因子。ALR的生物学作用主要表现在直接刺激肝细胞增殖和再生、对肝脏的保护作用、参与组织器官的形成与发育、**调控作用以及促肝癌细胞增殖等效应。s虽然肝再生增强因子有着重要生物学作用,但ALR究竟如何发挥生物学的调节机制，目前还不清楚
肝再生增强因子抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：细胞生物 信号转导 生长因子和**
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid