ENPP3蛋白抗体
规格：1mg/1ml
英文名： ENPP3
别名： ENPP3; CD203c; ectonucleotide pyrophosphatase/phosphodiesterase 3; RP5-988G15.3; B10; CD203c; NPP3; PD-IBETA; PDNP3; ENPP3_HUMAN.
分子量： 100kDa
储存液：0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glyce
克隆类型：Polyclonal
亚型：IgG
纯化方法：affinity purified by Protein A
**原：KLH conjugated synthetic peptide derived from human ENPP3
交叉反应：Human, Mouse, Rat, Dog, Pig, Cow,
细胞定位：细胞膜 分泌型蛋白
ENPP3蛋白抗体产品介绍：background: The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. Function: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. Subcellular Location: Membrane; Single-pass type II membrane protein ENPP3蛋白抗体(Potential). Secreted. Note=Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells. Tissue Specificity: Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors. Post-translational modifications: N-glycosylation is necessary for correct trafficking to the apical surface, but is not the apical targeting signal. It has been suggested that the active SMB domain may be ENPP3蛋白抗体permitted considerable disulfide bond heterogeneity or variability, thus two alternate disulfide patterns based on 3D structures are described with 1 disulfide bond conserved in both. Similarity: Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. Contains 2 SMB (somatomedin-B) domains. Gene ID: 5167 Database links: Entrez Gene: 5167 Human Entrez Gene: 5169 Human Omim: 602182 Human SwissProt: O14638 Human SwissProt: P22413 Human Unigene: 486489 Human Unigene: 527295 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. CD203c蛋白是一个糖基化的2型跨膜蛋白分子,CD203c的表达主要在嗜碱细胞、肥大细胞和它们的前体细胞上。
ENPP3蛋白抗体产品应用：WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:20-300 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
研究领域：**学 通道蛋白
储存条件： Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
来源： Rabbit
外观： Lyophilized or Liquid